JOURNAL ARCHIVE: 04/07/07 6:05 PM
Did I run 100 miles straight my first day after escaping the Libyans?
That hip injury must have been later. I doubt it was the Libyans that were going to chop me up with that cleaver. That did cut me up some, but it was a few months later I got hit in the hip with the cleaver knife.
[JOURNAL ARCHIVE 7 April 2007 excerpts ends]
http://en.wikipedia.org/wiki/Hammerhead_ribozyme
Hammerhead ribozyme
Hammerhead RNAs are RNAs that self-cleave via a small conserved secondary structural motif termed a hammerhead because of its shape. Most hammerhead RNAs are subsets of two classes of plant pathogenic RNAs: the satellite RNAs of RNA viruses and the viroids. The self-cleavage reactions, first reported in 1986, are part of a rolling circle replication mechanism. The hammerhead sequence is sufficient for self-cleavage and acts by forming a conserved three-dimensional tertiary structure.
In the natural state, a hammerhead RNA motif is a single strand of RNA, and although the cleavage is autocatalytic and takes place in the absence of protein enzymes, the hammerhead RNA itself is not a true enzyme in its natural state, as it cannot catalyze multiple turnovers.
In vitro hammerhead constructs can be engineered such that they consist of two RNA strands. The strand that gets cleaved can be supplied in excess, and multiple turnover can be demonstrated and shown to obey Michaelis-Menten kinetics, typical of protein enzyme kinetics. Such constructs are typically employed for in vitro experiments, and the term "hammerhead RNA" has become in practice synonymous with the more frequently used "hammerhead ribozyme".
The minimal hammerhead ribozyme sequence that is catalytically active consists of three base-paired stems flanking a central core of 15 conserved (mostly invariant) nucleotides, as shown. The conserved central bases, with few exceptions, are essential for ribozyme’s catalytic activity. Such hammerhead ribozyme constructs exhibit a turnover rate (kcat) of about 1 molecule/minute and a Km on the order of 10 nanomolar.
The hammerhead ribozyme is arguably the best-characterized ribozyme. Its small size, thoroughly-investigated cleavage chemistry, known crystal structure, and its biological relevance make the hammerhead ribozyme particularly well-suited for biochemical and biophysical investigations into the fundamental nature of RNA catalysis.
Hammerhead ribozymes may play an important role as therapeutic agents; as enzymes which tailor defined RNA sequences, as biosensors, and for applications in functional genomics and gene discovery.
JOURNAL ARCHIVE: 12/23/08 9:15 PM
From 10/26/1944 ( ) To 10/9/1971 ( ) is 9844 days
From 3/4/1959 ( ) To 2/14/1986 ( ) is 9844 days
From 10/26/1944 ( ) To 3/14/1965 ( ) is 7444 days
From 3/4/1959 ( ) To 7/21/1979 ( date hijacked from me:my wife Phoebe and I are married ) is 7444 days
http://bioguide.congress.gov/scripts/biodisplay.pl?index=C001061
CLEAVER, Emanuel, II, (1944 - )
CLEAVER, Emanuel, II, a Representative from Missouri; born in Waxahachie, Ellis County, Tex., October 26, 1944
elected as a Democrat to the One Hundred Ninth Congress and to the succeeding Congress (January 3, 2005-present).
[JOURNAL ARCHIVE 23 December 2008 excerpt ends]
"Space: Above And Beyond"
"Ray Butts"
22 October 1995
Episode 5 DVD video:
US Navy aircraft-spacecraft carrier Saratoga bridge communications officer: Commodore, I've got a bogey bearing two-niner-zero.
US Navy Commodore Ross: I.F.F.?
US Navy aircraft-spacecraft carrier Saratoga bridge communications officer: Negative, sir.
US Marine Corps Lieutenant Colonel T.C. McQueen: Scope me. It's a Hammerhead.
US Navy aircraft-spacecraft carrier Saratoga bridge communications officer: Still closing. Zero target aspect.
US Navy Commodore Ross: All our birds are accounted for, and there's no other ships in the region.
US Marine Corps Lieutenant Colonel T.C. McQueen: Any, um - Any intelligence reports of Chigs flying captured SA-43's?
US Navy aircraft-spacecraft carrier Saratoga bridge communications officer: He's headed right for us.
US Marine Corps Lieutenant Colonel T.C. McQueen: Could be a Silicate suicide bomber.
US Navy Commodore Ross: Deny it. Warn him.
US Navy aircraft-spacecraft carrier Saratoga bridge communications officer: Unidentified spacecraft off my port bow, you're approaching the U.S. naval carrier Saratoga. Request you alter course and identify yourself immediately. He's still coming, sir.
US Navy Commodore Ross: Fire a warning shot.
US Marine Corps Lieutenant Colonel T.C. McQueen: Two point six niner off the port bow.
US Navy aircraft-spacecraft carrier Saratoga bridge weapons officer: Two point six niner off the port bow. Aye-aye.
US Navy aircraft-spacecraft carrier Saratoga bridge communications officer: Commodore, it's overriden the H.B.D.L. It's docking.
US Navy Commodore Ross: Security alert! Master-of-arms, lay to the third deck.
US Navy aircraft-spacecraft carrier Intership communication: All security personnel, Code Red. All security personnel, Code Red.
US Marine Corps Lieutenant Colonel T.C. McQueen: Pop the canopy.
US Navy aircraft-spacecraft carrier Saratoga ship security force team member: He's dead.
US Marine Corps Lieutenant Colonel T.C. McQueen: Kind of a bummer getting your butt kicked by a dead guy.
http://www.cswap.com/1996/Star_Trek:_First_Contact/cap/en/25fps/a/01_00
Star Trek: First Contact
1:00:58
If it means nothing to you,
why protect it?
1:01:02
I am simply imitating
the behaviour of humans.
