Sunday, September 14, 2014

You've been a naughty little monkey, haven't you?




Yes, you have.










http://www.nobelprize.org/nobel_prizes/medicine/laureates/1997/prusiner.html

Nobelprize.org

The Official Web Site of the Nobel Prize


The Nobel Prize in Physiology or Medicine 1997

Stanley B. Prusiner

Born: 28 May 1942, Des Moines, IA, USA










http://www.imdb.com/title/tt0089092/releaseinfo

IMDb


Enemy Mine (1985)

Release Info

USA 20 December 1985










http://www.imdb.com/title/tt0089092/quotes

IMDb


Enemy Mine (1985)

Quotes


[opening narration]

Davidge: By late in the 21st century, the nations of the Earth were finally at peace, working together to explore and colonize the distant reaches of space. Unfortunately, we weren't alone out there.










http://www.itg.be/internet/ebola/ebola-24.htm


THE EPIDEMIOLOGY OF EBOLA HAEMORRHAGIC FEVER IN ZAIRE, 1976


The first known case, a 44-year old male instructor at the Yambuku Mission school, came to the Mission hospital on 26 August 1976 with a febrile illness felt due to malaria. He was given an injection of chloroquine at the dispensary. The fever dropped and remained normal over the next four days but rose to 39.2º on 1 September. The typical syndrome evolved from that day and he died on 8 September with severe haemorrhage.



http://www.independent.co.uk/life-style/health-and-families/features/ebola-epidemic-plagued-by-fear-9636462.html

THE INDEPENDENT


Ebola outbreak: Why has a disease that's only ever killed 2,000 people captivated the darkest side of our imagination?

Leigh Cowart Tuesday 29 July 2014

On 13 October 1976, Frederick A Murphy, a doctor of veterinary medicine, saw something that would terrify the masses for decades to come. A few days earlier, a box containing a specimen from a patient in Zaire had arrived at the Centers for Disease Control in Atlanta, Georgia, in poor condition, the glass tubes broken in transit. Rather than send it straight to the autoclave for sterilisation, his colleague, Dr Patricia Webb, scavenged some fluid-soaked cotton from the damaged delivery. After the virus spent a few days in tissue culture – monkey kidney cells, to be specific – Murphy prepared a sample for examination with an electron microscope.

When he saw it, the filamentous hook-and-loop formation now so recognisable, he immediately shut down the device. He had to return to where he prepared the sample. He had to bleach the area, to autoclave his equipment and his protective coverings. It was urgent.

Then he returned his attention to the sample. He thought he'd seen Marburg, a lethal filovirus capable of causing a viral hemorrhagic fever, and shot a film's worth of pictures – not realising he had, in fact, just become the first human to ever photograph the slender, looping tell of the Ebola virus.

Ebola. The name itself has become a synonym for horror. That a strand of 280 or so amino acids carrying little more than simple instructions and lucky keys for vertebrate locks can kill in such a fantastically gruesome manner is a testament to the ferocity of nature at the molecular core. It's one thing to fear life forms at the macro level – to dread the shark in the water, to gawk at lacerations rimmed by skin flapping around like party streamers, to see the stump and hear the story and be filled with awe at the efficiency of an ancient apex predator. It's quite another to contemplate your own body liquefying inside you, spilling through all of your available holes as you cling to life – to consider that something so deadly could have such stealth, present only in the bodily destruction it leaves in its wake.


There is perhaps no other disease that captivates the imagination quite like Ebola. It's served up as pure pop-culture nightmare fuel, from Richard Preston's The Hot Zone, the 1994 non-fiction thriller that chronicled the early days of Ebola, to the fictionalised monkey-hosted virus in 1995's Outbreak. Even The Walking Dead's zombies are of the infectious variety, bleeding from their dead eyes in between bites of human flesh. It's hard to imagine something worse than a virus that leaves people to die in the decaying wreckage of their own cytokine storm, bodies that leak with blood and death, commandeered and turned into Ebola replication machines.

No disrespect, of course, to death by starvation. Or cancer. Or measles.

Part of the horror of Ebola is that it shatters the idea of a "good death". You can't deny mortality when death is on display in this way: bodies disintegrating, the sounds and smells of hot, sick blood and feces and bile erupting and oozing from a not-yet corpse. There will be no one to cradle the deceased, no comments about how they "look so peaceful", like they're "just sleeping". There will not be a burial; there will be a disposal.

But Ebola, for all its evils, could actually be a whole lot worse. On 26 August 1976, a 44-year-old teacher appeared at Yambuku Mission Hospital in Zaire (now called the Democratic Republic of the Congo) with a fever and what he thought was malaria, and received an injection of the antimalarial drug chloroquine. At the time, the hospital had 120 beds and a medical staff of 17, and ran a clinic that treated 6,000 to 12,000 people monthly. Each morning, administrators issued five syringes and needles to the nursing staff, to be used in the outpatient department, the prenatal clinic and the inpatient wards. According to a report from the WHO, "syringes and needles were apparently not sterilised between their use on different patients but rinsed in a pan of warm water. At the end of the day they were sometimes boiled".

After the injection, the man's fever resolved quickly. On 1 September, it came back. He was admitted to the hospital four days later with gastrointestinal bleeding and died three days after that. By the end of September, when the hospital closed, 11 of its 17 staff members were dead.



http://www.biodesign.asu.edu/news/defensive-measures-toward-a-vaccine-for-ebola

ASU BIODESIGN INSTITUTE

ARIZONA STATE UNIVERSITY

December 05, 2011

On August 26, 1976, a time bomb exploded in Yambuku, a remote village in Zaire, (now the Democratic Republic of the Congo). A threadlike virus known as Ebola had emerged, soon earning a grim distinction as one of the most lethal, naturally occurring pathogens on earth, killing up to 90 percent of its victims, and producing a terrifying constellation of symptoms known as hemorrhagic fever.



http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153011/

NCBI

PMC

US National Library of Medicine

National Institutes of Health


Epidemiol Health. 2014; 36: e2014014.

Published online Aug 18, 2014. doi: 10.4178/epih/e2014014

PMCID: PMC4153011

What do we really fear? The epidemiological characteristics of Ebola and our preparedness

Moran Ki

Abstract.

Ebola virus disease (hereafter Ebola) has a high fatality rate; currently lacks a treatment or vaccine with proven safety and efficacy, and thus many people fear this infection. As of August 13, 2014, 2,127 patients across four West African countries have been infected with the Ebola virus over the past nine months. Among these patients, approximately 1 in 2 has subsequently died from the disease. In response, the World Health Organization has declared the Ebola outbreak in West Africa to be a Public Health Emergency of International Concern. However, Ebola is only transmitted by patients who already present symptoms of the disease, and infection only occurs upon direct contact with the blood or body fluids of an Ebola patient. Consequently, transmission of the outbreak can be contained through careful monitoring for fever among persons who have visited, or come into contact with persons from, the site of the outbreak. Thus, patients suspected of presenting symptoms characteristic of Ebola should be quarantined. To date, South Korea is not equipped with the special containment clinical units and biosafety level 4 facilities required to contain the outbreak of a fatal virus disease, such as Ebola. Therefore, it is necessary for South Korea to make strategies to the outbreak by using present facilities as quickly as possible. It is also imperative that the government establish suitable communication with its citizens to prevent the spread of uninformed fear and anxiety regarding the Ebola outbreak.

The current Ebola epidemic has garnered wide media attention throughout the world. As a result, many people fear that the disease, which is generally limited to the African continent, may cause an outbreak in their local community at any given moment.

The present paper will examine the epidemiological characteristics of Ebola, our level of preparedness, and discuss what we fear.

Ebola is a viral disease. Although it has previously been referred to as “Ebola hemorrhagic fever,” some Ebola patients did not present hemorrhage, and thus, it is now referred to as Ebola virus disease. The first known Ebola patient was a 44-year old man who had managed the construction of a school in northern Zaire (currently the Democratic Republic of Congo, DRC). On August 26, 1976, the patient presented at a hospital with a high fever. He received an injection of chloroquine for presumptive malaria and had a clinical remission of his symptoms the next four days. On the sixth day, the patient had a fever of 39.2°C and began to hemorrhage. On September 8 (the 14th day), the patient died with severe hemorrhage. For the following months, until late-October, there was an outbreak of Ebola, with 280 of the 318 patients subsequently dying from the disease [1].

Unfortunately, in the hospital that treated the first case of Ebola, all 17 hospital employees were exposed to the patient, resulting in 13 being infected, and 11 dying. When the pathway of infection for this outbreak was examined, 85 of the 318 patients (26.7%) were found to have received an injection at their respective hospitals. There were no survivors among the patients who were infected through injections. At the time, syringes and needles were sometimes rinsed between patients in a pan of warm water. At the end of the day they were sometimes boiled [1].

When this outbreak was investigated to determine the source of the infection, no particular behavior of interest was presented by the first case prior to infection. Although the patient purchased, cooked, and ate bushmeat (antelopes), other members of his party who had touched and eaten the same bushmeat had not contracted Ebola. During the search through the hospital’s records from January 1974 to the beginning of the epidemic, only one case resembled Ebola. This case was an adult man who was hospitalized on August 20, 1976, with “epistaxis and diarrhea.” The person left against medical advice on August 30, and could not be found, despite an active search during the investigations [1]. It is possible that the first Ebola case was injected using a contaminated syringe or needle that had been used to treat the patient with “epistaxis and diarrhea.”

Since then, Ebola outbreaks have occurred from time to time in Africa over the past 38 years. In this time, there have been 19 additional outbreaks, primarily in central African countries including the DRC (1977, 1995, 2007, 2008, and 2012), Sudan (1976, 1979, and 2004), Gabon (1994, 1996, 2001, and 2002), Uganda (2000, 2007, and 2012), and the Congo (2001-2002, 2003, and two in 2005). There have been 2,403 patients affected during these 19 outbreaks, and 1,594 patients have died from Ebola (66.3%). Although the fatality rate varies depending on the outbreak, country, virus, and period, the most recent outbreak in the DRC during 2012 had a fatality rate of 46.8%, which is a substantially lower than the initial Ebola outbreak (Figure 1).

The current Ebola epidemic is unique from the initial outbreak in West Africa, as it has broken the pattern of outbreaks typically occurring in Central Africa. Beginning in Guinea in December 2013, the present outbreak spread to Sierra Leone, Liberia, and Nigeria, and is now the largest outbreak in history.










http://www.presidency.ucsb.edu/ws/index.php?pid=86207

The American Presidency Project

Barack Obama

XLIV President of the United States: 2009 - present

Remarks at Nellis Air Force Base, Nevada

May 27, 2009

Thank you so much. Everybody please have a seat. Thank you so much. I've got some special acknowledgments that I have to make. First of all, we've got some members of the congressional delegation Nevada who are doing outstanding jobs not only for Nevada but also for the men and women in uniform. And so please give a warm welcome to Congresswoman Shelley Berkley, Congresswoman Dina Titus. And we're in his district, he couldn't be here, but Congressman Dean Heller, please give him a big round of applause.

I also want to thank the State controller, Kim Wallin, for her great work; the Nevada secretary of State, Ross Miller; Nevada State treasurer, Kate Marshall. I want to thank the Brigadier General, Stanley Kresge, for the wonderful, outstanding work that he does, as well as Colonel Dave Belote, who just gave me an outstanding tour of the solar panel facility out here. But mainly I want to thank all of you, the men and women in uniform, for your service to our country. We're grateful to you. Thank you.

I just spoke to a handful of your commanders here. I know some are about to be deployed to Iraq and Afghanistan, many have just come back. The fact that you serve each and every day to keep us safe is something that every American is grateful for. And so if I don't do anything else as your Commander in Chief, I'm going to make sure that we're there for you just as you've been there for us. So thank you very much.

Finally, let me acknowledge Senator Harry Reid, not just for the generous introduction, not only because he's been a great friend, not only because he's been an outstanding Majority Leader, but also because of everything that he's done for the people of Nevada and for the armed services. He is somebody who has never forgotten his roots. After all these years, he still brings the voices and values of Searchlight, Nevada to the Nation's most important debates in Washington, DC, and we are better off because he does. So please give Harry Reid a big round of applause.

You know, it's always a pleasure to get out of Washington a little bit. Washington is okay, but it's nice taking some time to talk to Americans of every walk of life outside of the Nation's Capital. And there's nothing like a quick trip to Vegas in the middle of the week. Like millions of other Americans, we come to this beautiful city for the sights and for the sounds. And today we come for the sun, because right now, we're standing near the largest solar electric plant of its kind in the entire Western Hemisphere--the entire Western Hemisphere. More than 72,000 solar panels built on part of an old landfill provide 25 percent of the electricity for the 12,000 people who live and work here at Nellis, that's the equivalent of powering about 13,200 homes during the day.

It's a project that took about half a year to complete, created 200 jobs, and will save the United States Air Force, which is the largest consumer of energy in the Federal Government, nearly $1 million a year. It will also reduce harmful carbon pollution by 24,000 tons per year, which is the equivalent of removing 4,000 cars from our roads. And most importantly, this base serves as a shining example of what's possible when we harness the power of clean, renewable energy to build a new, firmer foundation for economic growth.

Now, that's the kind of foundation we're trying to build all across America.










From 8/3/1998 ( Tom Clancy "Rainbow Six" ) To 5/27/2009 is 3950 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 8/26/1976 ( the first known case of Ebola ) is 3950 days



From 9/26/1962 ( premiere US TV series "The Beverly Hillbillies"::series premiere episode "The Clampetts Strike Oil" ) To 4/20/2006 ( Stanley Hiller dead ) is 15912 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 5/27/2009 is 15912 days



From 6/25/1947 ( "The Diary of a Young Girl" by Anne Frank is first published ) To 1/17/1991 ( the date of record of my United States Navy Medal of Honor as Kerry Wayne Burgess chief warrant officer United States Marine Corps circa 1991 also known as Matthew Kline for official duty and also known as Wayne Newman for official duty ) is 15912 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 5/27/2009 is 15912 days



From 6/25/1947 ( "The Diary of a Young Girl" by Anne Frank is first published ) To 1/17/1991 ( RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 - the Persian Gulf War begins as scheduled severe criminal activity against the United States of America ) is 15912 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 5/27/2009 is 15912 days



From 6/25/1947 ( Jimmie Walker ) To 1/17/1991 ( the date of record of my United States Navy Medal of Honor as Kerry Wayne Burgess chief warrant officer United States Marine Corps circa 1991 also known as Matthew Kline for official duty and also known as Wayne Newman for official duty ) is 15912 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 5/27/2009 is 15912 days



From 6/25/1947 ( Jimmie Walker ) To 1/17/1991 ( RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 - the Persian Gulf War begins as scheduled severe criminal activity against the United States of America ) is 15912 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 5/27/2009 is 15912 days



From 11/12/1992 ( Ford Motor Company announces the retirement of president Philip Benton ) To 5/27/2009 is 6040 days

6040 = 3020 + 3020

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 2/8/1974 ( premiere US TV series "Good Times" ) is 3020 days



From 6/25/1996 ( premiere US film "Independence Day" ) To 5/27/2009 is 4719 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 10/4/1978 ( premiere US TV series pilot "B.J. and the Bear" ) is 4719 days



From 3/16/1991 ( my first successful major test of my ultraspace matter transportation device as Kerry Wayne Burgess the successful Ph.D. graduate Columbia South Carolina ) To 5/27/2009 is 6647 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 1/14/1984 ( Ray Kroc dead ) is 6647 days



From 5/28/1942 ( Stanley Prusiner ) To 12/20/1985 ( premiere US film "Enemy Mine" ) is 15912 days

From 11/2/1965 ( my birth date in Antlers Oklahoma USA and my birthdate as the known official Deputy United States Marshal Kerry Wayne Burgess and active duty United States Marine Corps officer ) To 5/27/2009 is 15912 days



[ See also: To Be Continued? ]



http://www.presidency.ucsb.edu/ws/index.php?pid=86231

The American Presidency Project

Barack Obama

XLIV President of the United States: 2009 - present

Remarks at a Democratic National Committee Fundraiser in Beverly Hills, California

May 27, 2009


It is good to be back in L.A. My main task here tonight is just to say thank you. First of all, I want to thank so many of you who were knocking on doors and making phone calls and traveling to other cities, turning an election into a movement, a movement for change.

But the fact that you're here tonight indicates that you understand the campaign just gave us a chance to bring about change. It didn't actually deliver the change, it gave us the chance, the opportunity; it put us in place to bring about change. So now the hard part starts.

So I decided I should come back to Los Angeles with all my great supporters--[applause]--and just to give you a little progress report, just a little progress report.

We started off in the midst of the worst economic crisis since the Great Depression. And so what we decided to do was pass the largest economic recovery package in the history of the United States of America, and we got it done in one month. All across America you've got folks who are going to work rebuilding roads and bridges, but also building an electric grid that can help move renewable energies from production to conception, saving teachers' jobs that might have been eliminated if we hadn't passed it, making sure that folks who lose their jobs still have health care, providing a whole host of support services to communities that were in need.

Then we signed something called the Lilly Ledbetter Act because we thought it made sense that women should get equal pay for equal work--I don't know if you agree with that. We removed the ban on funding stem cell research because we believe in the possibilities of science.

What else did we do? [Laughter]










http://www.britannica.com/EBchecked/topic/1239247/Stanley-Hiller-Jr

Encyclopædia Britannica


Stanley Hiller, Jr.

(born Nov. 15, 1924, San Francisco, Calif.—died April 20, 2006, Atherton, Calif.), American helicopter designer who , was a teenager when he founded his own company, Hiller Industries, which made a handsome profit from the manufacture of the Comet, a miniature model racing car that he designed; the firm was transformed into a million-dollar business when the 16-year-old college student was contracted by the U.S. military to make parts for combat aircraft during World War II. Hiller, with the backing of his father, left college to concentrate on designing the XH-44, a coaxial helicopter (the first to feature two blades spinning in opposite directions). He later founded United Helicopters (later Hiller Aircraft Corp.). Among his other inventions were the Rotomatic Control System, the one-man Rotocycle, the Flying Platform, the Hornet, and the X-18 tilt-wing transport. Hiller later established an investment company that specialized in helping failing companies make a turnaround. In 2002 he was the recipient of the Smithsonian Institution’s National Air and Space Museum Trophy for Lifetime Achievement.










http://www.cswap.com/1996/Independence_Day/cap/en/2_Parts/a/01_04

Independence Day


1:05:19
Hope you got an airbag!










http://www.snpp.com/episodes/8F06.html

Lisa's Pony


Burns: Muhahahahaha... Ahem. Sorry, I was just um, eh, um, thinking of something funny Smithers did today.

Smithers: I didn't do anything funny today.

Burns: [hand over mouth] Shut! up!










http://www.e-reading.org.ua/bookreader.php/71211/Clancy_-_Rainbow_Six.html


Tom Clancy

Rainbow Six


CHAPTER 6

TRUE BELIEVERS


"So, what do you do, Mark?"

"Molecular biochemistry, Ph.D., in fact."

"What's that mean?"

"Oh, figuring out how life happens. Like how does a bear smell so well," he went on, lying. "It can be interesting, but my real life is coming out to places like this, hunting, meeting people who really understand the game better than I do. Guys like you," Mark concluded, with a salute of his glass. "What about you?"

"Ah, well, retired now. I made some of my own. Would you believe geologist for an oil company?"

"Where'd you work?"

"All over the world. I had a good nose for it, and the oil companies paid me a lot for finding the right stuff, y'know? But I had to give it up. Got to the point-well, you fly a lot, right?"

"I get around," Mark confirmed with a nod.

"The brown smudge," Foster said next.

"Huh?"

"Come on, you see it all over the damned world. Up around thirty thousand feet, that brown smudge. Complex hydrocarbons, mainly from passenger jets. One day I was flying back from Paris - connecting flight from Brunei, I came the wrong way 'round 'cuz I wanted to stop off in Europe and meet a friend. Anyway, there I was, in a fuckin'747, over the middle of the fucking Atlantic Ocean, like four hours from land, y'know? First-class window seat, sitting there drinking my drink, lookin' out the window, and there it was, the smudge - that goddamned brown shit, and I realized that I was helpin' make it happen, dirtyin' up the whole fuckin' atmosphere.



- posted by H.V.O.M - Kerry Wayne Burgess 07:29 AM Pacific Time Spokane Valley Washington USA Sunday 14 September 2014