Thursday, February 21, 2013
Genome $cience$
From: Kerry Burgess
Sent: Tuesday, February 12, 2013 5:58 AM
To: 'Chad Trammell'
Subject: RE: Genome $cience$
http://community.seattletimes.nwsource.com/archive/?date=20030822&slug=waterston22
The Seattle Times Search
Friday, August 22, 2003
Q&A: Critical mass forming for UW genetic research
By Luke Timmerman
Seattle Times business reporter
Robert Waterston made his name as a leader of the Human Genome Project, the historic job that put the genetic instruction book on the desktop of all biologists.
These days, Waterston is settling in as a Seattleite. He bicycles to work down the Burke-Gilman Trail
JOURNAL ARCHIVE: Thursday, October 09, 2008 Posted by H.V.O.M at 2:07 PM
I remember well that day 2/1/2002. I was riding my bicycle from Bellevue, Washington, along the regular route I followed to the office I worked at in the Microsoft building in Issaquah, Washington. I was crossing a small bridge next to the Costco building in Issaquah and within sight of the Microsoft building when my bicycle literally flipped end-over-end and I went face first into the concrete sidewalk. I was left sprawled out on my back on the sidewalk among the wooded area of that bridge and dazed for a few minutes. I got up after a few minutes and rode my bicycle the remaining mile or so to the office and noticed a short time later that I had a black eye forming from where my left eye brow seemed to have hit the concrete just before my helmet absorbed the rest of the impact which was painful in itself to my head. I would later think that someone had caused that accident to happen and that it was something similar to that scene in the 1963 film "The Great Escape" where Steve McQueen stretches the thin wire across the road to knock the German soldier off his motorcycle.
[JOURNAL ARCHIVE 9 October 2008 excerpt ends]
http://maps.google.com/?ll=47.552026,-122.056805&spn=0.001617,0.004128&t=m&z=19&layer=c&cbll=47.552024,-122.057487&panoid=x0XRMD3vULY_p9aiGTGpKw&cbp=12,356.15,,1,11.18
1171 Northwest Sammamish Road, Washington, United States
http://articles.latimes.com/2003/feb/02/nation/na-main2
Los Angeles Times
'COLUMBIA IS LOST'
Shuttle Burns Up Over Texas, Killing All 7 Crew Members
February 02, 2003|Scott Gold | Times Staff Writer
HOUSTON — The space shuttle Columbia, flying at 18 times the speed of sound, disintegrated in a rumbling roar and incandescent flashes of light Saturday over East Texas, killing all seven of its astronauts and scattering chunks of metal and machinery across two states, only 16 minutes before its scheduled landing at Cape Canaveral, Fla.
It sounded like "rolling thunder," one witness said. Shock waves rattled homes and barns 39 miles below. Bright objects hurtled off the spacecraft, and the debris plummeted to Earth. Pieces were soaked with toxic fuel. Some were in flames and started several brush fires. Plumes of chalk-white smoke streaked across the blue sky, visible from Texas to Mississippi.
Officials warned people in East Texas and northwestern Louisiana not to touch the toxic debris. No injuries were reported on the ground. There was at least one report of human remains from the shuttle, recovered in Hemphill, Texas, near the Louisiana line. A hospital employee on his way to work told authorities he found body parts near some debris.
http://www.divxmoviesenglishsubtitles.com/H/Hunt_For_Red_October_CD1.html
Hunt For Red October [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
And today is the first anniversary
of his wife's death.
Come on. You're just an analyst.
How can you read his mind?
I know Ramius, General.
He's nearly a legend in the submarine community.
He's been a maverick his entire career.
I actually met him once at an embassy dinner.
Have you ever met Captain Ramius, General?
http://www.imdb.com/title/tt0099810/quotes
IMDb
The Internet Movie Database
Memorable quotes for
The Hunt for Red October (1990) [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
Jeffrey Pelt: You slammed the door on the General pretty hard, didn't you?
Jack Ryan: That was not my intention.
Jeffrey Pelt: Oh, yes, it was! He was patronizing you, and you stomped on him! And in my opinion, he deserved it!
http://dictionary.reference.com/browse/probable+cause
Dictionary.com
probable cause
Law. reasonable ground for a belief, as, in a criminal case, that the accused was guilty of the crime
law reasonable grounds for holding a belief, esp such as will justify bringing legal proceedings against a person
http://dictionary.reference.com/browse/arrest
Dictionary.com
arrest
the taking of a person into legal custody, as by officers of the law.
http://community.seattletimes.nwsource.com/archive/?date=20030822&slug=waterston22
The Seattle Times Search
Friday, August 22, 2003
Q&A: Critical mass forming for UW genetic research
These days, Waterston is settling in as a Seattleite. He bicycles to work down the Burke-Gilman Trail
http://dictionary.reference.com/browse/admission
Dictionary.com
admission
confession of a charge, an error, or a crime; acknowledgment: His admission of the theft solved the mystery.
a confession, as of a crime
From: Kerry Burgess
Sent: Tuesday, February 12, 2013 5:45 AM
To: 'Chad Trammell'
Subject: Genome $cience$
Having watched all but the final 20 minutes of the "Star Trek: Voyager" series premiere episode (a hand breaks through underground to the baked desert surface) I wonder about the possibilities of immortality to the human mind thus I decided to transmit across the wire a small preview of an observation I have been working on (of predictable results if you study my previous reports) and that a few hours ago I had decided I might not ever finish working on it or any other.
Distant memories. If a human being could live four hundred years then how would he remember his life centuries earlier.
But then I flout that notion because why do I remember 1988 so well, comparatively speaking, and not so well the year 1989? A brain doctor could tell you. I cannot. Maybe it's time for me to start figuring out how to try.
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19 meeting, approved the consolidation of the Department of Genetics in the College of Arts and Sciences and the Department of Molecular Biotechnology in the School of Medicine. The merger creates the new Department of Genome Sciences in the School of Medicine.
http://www.tv.com/shows/quantum-leap/genesis-1-60487/
tv.com
Quantum Leap Season 1 Episode 1
Genesis (1)
September 13, 1956: Although the Project Quantum Leap isn't ready yet, Sam Beckett doesn't listen to supercomputer Ziggy, hops into the Accelerator and leaps.
AIRED: 3/26/89
http://www.tv.com/shows/cavalcade-of-america/the-marine-who-was-200-years-old-249386/
tv.com
Cavalcade of America Season 3 Episode 11
The Marine Who Was 200 Years Old
AIRED: 1/4/55
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19 meeting, approved the consolidation of the Department of Genetics in the College of Arts and Sciences and the Department of Molecular Biotechnology in the School of Medicine. The merger creates the new Department of Genome Sciences in the School of Medicine.
http://www.imdb.com/title/tt0336609/releaseinfo
IMDb
Release dates for
Husbands Won't Tell (1928)
Country Date
USA 29 August 1928
http://www.britannica.com/EBchecked/topic/1243193/Melinda-Gates
Encyclopædia Britannica
Melinda Gates
ARTICLE from the Encyclopædia Britannica
Melinda Gates, née Melinda Ann French (born Aug. 15, 1964, Dallas, Texas, U.S.), American businesswoman and philanthropist who—with her husband, Microsoft Corporation cofounder Bill Gates
http://www.imdb.com/name/nm2320473/bio
IMDb
The Internet Movie Database
Biography for
Melinda Gates
Date of Birth
15 August 1964
http://www.jsc.nasa.gov/Bios/htmlbios/husband.html
National Aeronautics and Space Administration
Lyndon B. Johnson Space Center
Houston, Texas 77058
Biographical Data
RICK DOUGLAS HUSBAND (COLONEL, USAF)
NASA ASTRONAUT
Died on February 1, 2003 over the southern United States when Space Shuttle Columbia and the crew perished during entry, 16 minutes prior to scheduled landing.
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19 meeting, approved the consolidation of the Department of Genetics in the College of Arts and Sciences and the Department of Molecular Biotechnology in the School of Medicine. The merger creates the new Department of Genome Sciences in the School of Medicine.
http://www.imdb.com/title/tt0772739/releaseinfo
IMDb
Release dates for
The Bride's Mistake (1931)
Country Date
USA 1 March 1931
http://news.bbc.co.uk/onthisday/hi/dates/stories/february/1/newsid_3416000/3416589.stm
BBC
ON THIS DAY 1 February
2003: Columbia shuttle disintegrates killing seven
The US space shuttle Columbia has broken up as it re-entered the Earth's atmosphere killing all seven astronauts on board.
http://www.chron.com/news/nation-world/article/New-report-Doomed-astronauts-fought-to-save-1781475.php
Chron
New report: Doomed astronauts fought to save Columbia
Fliers' final moments on Columbia
Report details astronauts' efforts to save doomed shuttle and offers ways to avoid future losses of life
MARK CARREAU, Copyright 2008 Houston Chronicle | December 30, 2008
They were doomed already and did not know it.
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19 meeting, approved the consolidation of the Department of Genetics in the College of Arts and Sciences and the Department of Molecular Biotechnology in the School of Medicine. The merger creates the new Department of Genome Sciences in the School of Medicine.
http://www.imdb.com/title/tt0032198/releaseinfo
IMDb
Release dates for
Always a Bride (1940)
Country Date
USA 2 November 1940
http://community.seattletimes.nwsource.com/archive/?date=19960429&slug=2326562
The Seattle Times Search
Monday, April 29, 1996
Baby Girl Born To Gates, Wife -- She's Jennifer Katherine
AP
BELLEVUE - Microsoft Chairman Bill Gates has a new title: father.
His wife, Melinda French Gates, gave birth Friday night
They named the baby Jennifer Katharine.
http://en.wikipedia.org/wiki/Ancient_technology_in_Stargate
Ancient technology in Stargate
From Wikipedia, the free encyclopedia
The Ancients (also known as "Alterans" and "Lanteans") are a fictional advanced race in the Stargate franchise, and are depicted as the precursor to modern-day humans. Their most notable creation in Stargate mythology is the entire Stargate network. Ancient science and technology, with a few exceptions, is shown as being superior to that of other races. The Ancients are portrayed as being extremely advanced in the areas of healing, power generation, and biology. They are also credited with designing a number of fictional weapons, primarily for use in the centuries-long war with the Wraith in the Pegasus Galaxy.
ATA Gene
The Ancient Technology Activation gene (ATA) is a specific gene present in all Ancients, and some of their human descendants, which acts as a key to much of their technology; if the user does not possess the gene, the technology will not activate. The ATA gene instructs various cells in the body to produce a series of proteins and enzymes that interact with the skin, nervous system, and brain, allowing the gene carriers to operate Ancient technology. Though rare naturally in most humans, Dr. Carson Beckett develops a retroviral gene therapy (using a deactivated mouse retrovirus) to transfer the Ancient gene expression to humans
http://community.seattletimes.nwsource.com/archive/?date=20030822&slug=waterston22
The Seattle Times Search
Friday, August 22, 2003
Q&A: Critical mass forming for UW genetic research
By Luke Timmerman
Seattle Times business reporter
Robert Waterston made his name as a leader of the Human Genome Project, the historic job that put the genetic instruction book on the desktop of all biologists.
These days, Waterston is settling in as a Seattleite. He bicycles to work down the Burke-Gilman Trail thinking of a new challenge: making sense of the flood of genetic data to improve human health.
Waterston, who turns 60 next month, came to the University of Washington in January to lead the department of genome sciences, which has three of the eight recognized leaders of the genome project. Last week, he broke ground on a $150 million state-of-the-art building to house his department and that of bioengineering. Nearly half the money for the building, a key recruiting tool, came from the Bill & Melinda Gates Foundation.
Waterston talked this week about what's next in genome research and why people who last studied biology in ninth grade will want to learn more. Here are excerpts:
Q: Why did you come to Seattle (from Washington University in St. Louis)?
A: The human genome was about complete. I thought the real challenge was in trying to figure out what all this sequence meant. I wanted to shift gears, and this place offered a real opportunity.
Q: You've said "this is the place" for future genomic research. Why?
A: This is a competitive business and lots of people have the idea of exploiting the genome. But the university and medical school here are committed. It is a broad-range university with strong engineering, and a strong clinical program. I think there's receptivity here to the idea that genomics can play a critical role in moving to the next level of patient care.
Q: When will we see your recruits arriving here?
A: The first will arrive in January. We'll get one or two a year. This infusion of young, enthusiastic people is going to be great.
Q: What does this place lack to get to a higher level?
A: Part of it is getting critical mass and an environment to stimulate each other's research. Part of it will be trying to organize clinical resources. We must have a much deeper understanding of the molecular biology of disease, and human variation is a path to that.
Q: A lot of people were swept up by the hype of genomics bringing an overnight medical revolution, and it didn't happen. How long can we realistically expect it to take before genomics benefits medicine?
A: It is going to be a revolution in medicine. I think what happened in the hype was the time frame got more and more compressed. People equated recovery of the genome sequence with therapy, and there are several steps between having the gene sequence and having an effective therapy. But it's already happening. (Progress) is not going to be overnight.
Q: What good is having genomic knowledge if there are no effective drugs for a disease?
A: If there's nothing that can be done, it is no good. For instance, there's a test for Huntington's, but nobody tests for it in Massachusetts because they've restricted their genetic testing to 30 diseases where something can be done. With cystic fibrosis, it's not clear (that) early diagnosis can lead to anything. But with Down syndrome, people get tested, and they can decide whether to carry a pregnancy to term.
Q: It sounds like people will have to become more informed to make good decisions.
A: Yes. The danger is (that) people will end up with a list that says 'If you don't do this, you'll have a 10 percent lower chance of dying at 70 of heart disease.' You'll be presented with a whole list of behavior modifications and a list of percentages applicable to you because of your genotype, and that's not very appealing.
Q: And there's always the worry of insurance companies getting ahold of that and using it to discriminate, right?
A: The ethical issues are enormous. There's also personal kinds of things, as in, what does having the knowledge do to you? With insurance, it's enormously challenging for society.
Q: How should this be handled?
A: It has to be done through better information, a more informed, more involved public. It is powerful information, and people will have to learn how to devise rules that will let it be used for good and not for evil.
Q: You've said the genome project benefited from free dissemination of results, without patents getting in the way. Industry fights any weakening of patents. What is the right way to balance the interests of science and business?
A: It's difficult. We have to recognize it is a balance. Industry won't invest sufficient funds to produce a therapy if they don't have monetary rewards at the end. But on the other hand, you don't have discoveries if there is not open dissemination. In my view, it's a matter of how far along in the discovery process a patent is granted and how broad-reaching the patent is. With patenting gene sequences, this information is at such a basic level, we can't begin to predict all the uses.
Q: How will the work in these labs create jobs in Seattle?
A: New technologies could lead to companies providing machines or services. The other way is through discoveries. If we discover a particular pathway has a major impact on (high blood pressure), and they begin to understand molecules involved, and they develop a patent position, they can start companies.
Q: What should the public, most of which dimly recalls ninth-grade biology, be doing to learn about this new biology that is changing health care and the economy?
A: They have to read. Seriously. A lot of biology is very complex, and depends on detailed understanding, but the great thing about DNA is (that) it's conceptually straightforward. People understand it's a language, with A, G, C and T, and different combinations have different meanings, just like words.
Q: What is the biggest obstacle to genome-science progress?
A: People's participation. Regulations protecting people's rights should not be so cumbersome and onerous (that) they prevent science. This is important. We have to have access to people with different variants. We have to do it fairly so they're not exploited or disadvantaged by participation in a study. But I worry we're going to create barriers to use of people's DNA that they themselves aren't concerned about.
Q: Does this mean we'll see more clinical trials done overseas?
A: Not just trials. This is for the discovery process, too. If the regulatory protections become unreasonable, and scientists in other countries will not be burdened, they will have better opportunities.
Q: Academia always complains about lacking money. Industry has to make short-term profit, making it hard to invest in research. What is the best way to pay for this work?
A: A lot will have to be government funded. It is such a fundamental nature that the payoff isn't obvious. And a lot of diseases will be rare. There won't be enough of a market for drugs.
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19 meeting, approved the consolidation of the Department of Genetics in the College of Arts and Sciences and the Department of Molecular Biotechnology in the School of Medicine. The merger creates the new Department of Genome Sciences in the School of Medicine.
http://www.tv.com/shows/stargate-sg-1/children-of-the-gods-1-7319/
tv.com
Stargate SG-1 Season 1 Episode 1
Children of the Gods (1)
The System Lord Apophis launches an attack through the Stargate, tucked away by the military after the events of the movie, and the SGC program is reactivated and given a new objective - seek out and find the alien invaders and defeat them. Jack O'Neill is called out of retirement and sent to locate Daniel Jackson on Abydos.
AIRED: 7/27/97
http://www.imdb.com/title/tt0066026/releaseinfo
IMDb
Release dates for
MASH (1970)
Country Date
USA 25 January 1970 (New York City, New York)
http://www.washington.edu/news/archive/id/2658
UNIVERSITY of WASHINGTON [ RACKETEER INFLUENCED AND CORRUPT ORGANIZATIONS US Title 18 ]
2001-10-31
UW consolidates departments to form Department of Genome Sciences
The UW Board of Regents, at its Oct. 19 meeting, approved the consolidation of the Department of Genetics in the College of Arts and Sciences and the Department of Molecular Biotechnology in the School of Medicine. The merger creates the new Department of Genome Sciences in the School of Medicine.
http://www.tv.com/shows/perry-mason/the-case-of-the-angry-astronaut-79534/
tv.com
Perry Mason Season 5 Episode 25
The Case of the Angry Astronaut
AIRED: 4/7/62
http://www.royal.gov.uk/HMTheQueen/Earlylife/Earlylife.aspx
The official website of The British Monarchy
The Queen's Early Life
The Queen was born at 2.40am on 21 April 1926
http://dictionary.reference.com/browse/genome
Dictionary.com
genome
a full set of chromosomes; all the inheritable traits of an organism.
From: Kerry Burgess
Sent: Tuesday, February 12, 2013 12:13 AM
To: 'Kerry Burgess'
Subject: RE: I am outsmarting myself.
That really means I have got to stop.
I keep going because I feel that is expected of me and that realization should be a warning to my mind.
To use the “Wraith” from “Stargate” as an expression that represents reality then they are manipulating us all into doing that stuff.
Those “Wraith” in reality caused all that to happen and they want me to recognize them.
There is only one way I know for certain that I could be free from their control: killing myself.
From: Kerry Burgess
Sent: Monday, February 11, 2013 10:57 PM
To: 'Kerry Burgess'
Subject: RE: I am outsmarting myself.
So that would mean everything I am doing is in support of that initiative.
That would explain why I am addicted to the work I am doing every day.
I must have known though when I started to outsmart myself that I would reach the point where I would stop.
From: Kerry Burgess
Sent: Monday, February 11, 2013 10:55 PM
To: 'Kerry Burgess'
Subject: I am outsmarting myself.
That’s what’s happening.
I am outsmarting myself.
I had to do that so that my superior intelligence doesn’t start running away into thoughts of superior intelligence.
By causing myself to dumb down I know that my superior intelligence is not causing things to happen that I am trying to narrow down.
- posted by H.V.O.M - Kerry Wayne Burgess 05:35 AM Pacific Time Seattle USA Thursday 21 February 2013
